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The history of arsenical pesticides and health risks related to the use of Agent Blue

Arsenicals in agriculture. Beginning in the 1970s, the use of arsenic compounds for such purposes as wood preservatives, began to grow. By 1980, in the USA, 70% of arsenic had been consumed for the production of wood preservatives. This practice was later stopped, due to the US Environmental Protection Agency (EPA) ban of the […]

Identifying populations sensitive to environmental chemicals by simulating toxicokinetic variability

The thousands of chemicals present in the environment (USGAO, 2013) must be triaged to identify priority chemicals for human health risk research. Most chemicals have little of the toxicokinetic (TK) data that are necessary for relating exposures to tissue concentrations that are believed to be toxic. Ongoing efforts have collected limited, in vitro TK […]

Another Chemistry Joke

Hexachlorobutadiene

Hexachlorobutadiene, also known as HCBD, perchlorobutadiene, or Dolen-Pur, is a colourless liquid with the molecular formula C4Cl6. It has a turpentine-like odour and does not evaporate or burn easily. It is not known how it tastes or at what level people can taste it. Hexachlorobutadiene does not occur naturally in the environment. It is […]

The asbestos fibre burden in human lungs: new insights into the Chrysotile debate

The traceability of asbestos fibres in human lungs is a matter of discussion especially for chrysotile. This issue is of high significance for differential diagnosis, risk assessment and occupational compensation. At present no intra-individual longitudinal information is available. This study addresses the question whether the asbestos fibre burden in human lungs decreases with time […]

Routine assessment of occupational exposure and its relation to semen quality in infertile men: a cross-sectional study

Concerns about the detrimental effects of occupational and environmental exposure on male reproductive function have been raised by reports of declining sperm quality over the last decades. The aim of this study was to investigate the association between altered semen parameters and exposure to occupational risk factors as assessed by questionnaire. The authors conducted […]

Toddler exposure to flame retardant chemicals: Magnitude, health concern and potential risk- or protective factors of exposure: Observational studies summarised in a systematic review

Endocrine disrupting flame retardant (FR) chemicals form a human health concern, that is investigated mostly from the perspective of adult- and early life exposure. No overview of studies on toddler exposure and health effects exist. However, toddlerhood is a critical developmental period and toddlers are at increased risk for exposure because of their age-specific […]

Heavy alcohol consumption increases the risk of active tuberculosis in Taiwanese adults: a nationwide population-based cohort study

This study investigated the impact of alcohol exposure on tuberculosis (TB) development in Taiwanese adults. Participants from the Taiwan National Health Interview Survey. Alcohol consumption and other covariates were collected by in-person interviews at baseline. Incident cases of active TB were identified from the National Health Insurance database. A multivariable Cox regression model was […]

Determination of polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans, and dioxin-like polychlorinated biphenyls in human serum using programmable-temperature vaporisation gas chromatography with high-resolution mass spectrometry

The determination of polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans, and dioxin-like polychlorinated biphenyls in blood from non-occupational population is essential for the investigation of adverse health effects from these pollutants. In this study, a sensitive method based on programmable-temperature vaporisation with large-volume injection coupled with gas chromatography with high-resolution mass spectrometry was developed to determine […]

Global Burden of Disease of Mercury Used in Artisanal Small-Scale Gold Mining

Artisanal small-scale gold mining (ASGM) is the world’s largest anthropogenic source of mercury emission. Gold miners are highly exposed to metallic mercury and suffer occupational mercury intoxication. The global disease burden as a result of this exposure is largely unknown because the informal character of ASGM restricts the availability of reliable data. In this […]