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Allyl Chloride

Allyl chloride is the organic compound with the molecular formula C3H5Cl. [1] It is a colourless, light yellow or amber liquid with an unpleasant pungent odour. It is highly flammable. [2] Allyl chloride is slightly soluble in water and miscible with alcohol, chloroform, ether, and petroleum ether. In the United States, allyl chloride is […]

Maternal exposure to ambient air pollution and risk of early childhood cancers: A population-based study in Ontario, Canada

There are increasing concerns regarding the role of exposure to ambient air pollution during pregnancy in the development of early childhood cancers. This population based study examined whether prenatal and early life (

Temporal trends of polychlorinated biphenyls serum levels in subjects living in a highly polluted area from 2003 to 2015: a follow-up study

A chemical factory located in Brescia, an industrialised town in North Italy, produced polychlorinated biphenyls (PCBs) since the 1930s to the 1980s, determining a relevant pollution of soil, food and people. Since 2001, following a survey carried out in the general population living in the town, the individuals with PCB serum levels higher than […]

Identification of chemical mixtures to which Canadian pregnant women are exposed: The MIREC Study

Depending on the chemical and the outcome, prenatal exposures to environmental chemicals can lead to adverse effects on the pregnancy and child development, especially if exposure occurs during early gestation. Instead of focusing on prenatal exposure to individual chemicals, more studies have taken into account that humans are exposed to multiple environmental chemicals on […]

The Relations between Polycyclic Aromatic Hydrocarbons Exposure and 1-OHP Levels as a Biomarker of the Exposure

Polycyclic aromatic hydrocarbons (PAHs) are the products of incomplete combustion or pyrolysis of various organic materials. Their ubiquity in the environment leads to measurable levels of exposure. However, the exposure varies strongly between different regions in Europe. Some PAHs with four or more rings are suspected to be human carcinogens. Therefore, the occupational and/or […]

Cancer incidence among capacitor manufacturing workers exposed to polychlorinated biphenyls

The authors evaluated cancer incidence in a cohort of polychlorinated biphenyl (PCB) exposed workers. Incident cancers, identified using state registries, were compared to those in a national population using standardised incidence ratios. Trends in prostate cancer incidence with cumulative PCB exposure were evaluated using standardised rate ratios and Cox regression models. For selected sites, […]

Cancer incidence in cohorts of workers in the rubber manufacturing industry first employed since 1975 in the UK and Sweden

Increased cancer risks have been reported among workers in the rubber manufacturing industry employed before the 1960s, but it is unclear for workers hired subsequently. The present study focused on cancer incidence among rubber workers first employed after 1975 in Sweden and the UK. Two cohorts of rubber workers employed for at least 1 […]

Do occupational exposures to vinyl chloride cause hepatocellular carcinoma and cirrhosis?

Controversy exists about the association between occupational exposures to vinyl chloride and hepatocellular carcinoma and cirrhosis. Two large multicentre mortality cohort studies, one American and another European, reported higher mortality for primary cancer of liver and biliary tract. However, the American study was not able to rule out misclassification, because based on death certificates […]

Varied exposure to carcinogenic, mutagenic, and reprotoxic (CMR) chemicals in occupational settings in France

This study explored varied exposure to carcinogenic, mutagenic, and reprotoxic chemicals (CMR) for French employees. The authors assessed data from the French national cross-sectional survey of occupational risks (SUMER) that was conducted in 2010 in a national representative sample of employees. Twenty-eight CMR agents that were classified by the International Agency for Research on […]

Occupational exposure to pesticides, reproductive hormone levels and sperm quality in young Brazilian men

The association of occupational exposure to current-use pesticides with reproductive hormones, semen quality, and genital measures was investigated among young men in the South of Brazil. A cross-sectional study was conducted in 99 rural and 36 urban men aged 18-23 years. Information on pesticide use was obtained through questionnaire. Serum and semen samples were […]