(1) Removal of lime or calcium salts, chiefly tricalcium phosphate, from bones and teeth, either in vitro or in vivo as a result of a pathologic process. (2) Precipitation of calcium from blood as by oxalate or fluoride, or the conversion of blood calcium to an un-ionized form as by citrate, thus preventing or delaying coagulation. [L. de-, away, + calx (calc-), lime, + facio, to make]